Thyroid Peroxidase Antibody

Additional Info: This test is also known as “Anti-Microsomal Antibody” and “Microsomal Antibody”. Used in diagnosis of hypothyroidism and thyroiditis.

Approximately 95% of patients with diffuse goiter, hypothyroidism, or both have Anti-TPO. Anti-TPO is especially useful with patients with subclinical hypothyroidism (elevated TSH and normal free T4 concentrations). Many of these patients will develop hypothyroidism.

Useful For:
It is recommended that both Thyroglobulin (antibody) and Thyroid Peroxidase Antibody be ordered together as in Thyroid Antibody Group, Serum since autoimmune thyroiditis may demonstrate a response to antigens other than thyroid microsomes.

Methodology: Chemiluminescence

Specimen Requirements:
1 yellow-top SST tube (minimum: 1.0 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.

Analytical Time: 2 days

Days Set Up: Monday through Friday

CPT Information:
86376 –