Protein C-Resistance, Activated

Useful For: Individuals with APC have a high risk of developing venous thrombosis.

Methodology: RVVT-Based Clot Assay

Specimen Requirements: 1 blue-top (citrate) tube (minimum: the remaining platelet poor plasma separated from 2.7 mL whole blood). Centrifuge blue-top soon after collection. Separate plasma and FREEZE immediately. Send specimen frozen in plastic vial.


  • If using a butterfly collection set, fill a 1 mL waste tube prior to blue-top. This ensures full blood volume in blue-top.
  • Draw specimen by vacuum. Do not over-fill the tube.
  • Hemolyzed specimens are not acceptable.
  • Tube must be filled to capacity.

Analytical Time: 2 days

Days Set Up: Monday through Saturday

CPT Information:
85307 –