Acetylcholine Receptor Binding Ab, Serum

Additional Info: Myasthenia gravis (MG) is a neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. This assay aids in the differential diagnosis of MG-like muscle weakness, in differentiating between generalized MG and ocular MG, and in monitoring therapeutic response. If binding antibodies are negative, blocking and modulating antibodies should be considered.

Methodology: Radioimmunoassay

Stat: 2-3 days

Specimen Requirements: 1 yellow-top SST tube (minimum: 0.5 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.

NOTE: Sample that are contaminated, hemolyzed, lipemic, icteric, or contain radioactive compounds from in vivo testing are unacceptable.

Days Set Up: Tuesday through Saturday

CPT Information:
83519 –