Anti-endomysial antibodies (EMA) are highly specific and sensitive markers for celiac disease. Recently the specific endomysial antigen has been identified as the protein crosslinking enzyme known as tissue transglutaminase (tTG).
Tissue Transglutaminase Antibody, IgA is useful in diagnosing gluten-sensitive enteropathies, such as celiac sprue, and an associated skin condition, dermatitis herpetiformis.
Methodology: Enzyme Immunoassay (EIA)
Specimen Requirements: 1 yellow-top SST tube (minimum: 0.5 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.
Gross hemolysis is unacceptable.
Lipemia and microbial contamination may affect results.
Analytical Time: 2 days
Days Set Up: Monday through Friday