If antibody is positive, the titer, considered medically appropriate will be reflexed, resulting in additional charges.
Smooth Muscle Antibodies are detected in 85% of Chronic Active Hepatitis cases and in less than 50% of Primary Biliary Cirrhosis cases but are usually negative in Extrahepatic Biliary Obstruction, Drug-Induced Liver Disease, Viral Hepatitis, and Hepatoma.
Methodology: Immunofluorescent Assay (IFA)
Specimen Requirements: 1 yellow-top SST tube (minimum: 0.1 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.
NOTE: Gross hemolysis and lipemia may affect results.
Analytical Time: 2 days
Days Set Up: Monday through Friday
CPT Reflex: Reflex Code: 86256- titer