Lyme Disease Screen (Confirmation IgG, IgM), Serum

Additional Info:

Western Blot confirmation (IgG, IgM) will automatically be performed if antibody is equivocal or positive. This further testing, considered medically appropriate, will be reflexed resulting in additional charges.

Useful For:
Recommended for early or unknown stage of Lyme Disease.

Lyme Disease was recognized in Lyme County, Connecticut in 1975. The disease is a multi-system disorder. It normally begins with Erythema Chronicus Migrans (ECM). This may be accompanied by headaches, fever, myalgia, arthralgias, stiff neck or lymphodenopathy. Patients often recover completely even without treatment. Untreated patients may suffer a recurrence of ECM or systemic involvement of the heart, nervous system, and/or joints. The disease is transmitted by a tick vector carrying Borrelia Burgdorferi. Specimens are screened by the EIA (Total Antibody) test and positive and indeterminate screen results are confirmed by retesting the specimen using the IgG and IgM Western Blot procedures.

Methodology: Enzyme Immunoassay (EIA)

Specimen Requirements:
1 yellow-top SST tube (minimum: 0.5 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.

• If early Lyme disease is suspected, recommend retesting in 2-4 weeks.
• Hemolysis, lipemia, and microbial contamination may affect results.

Analytical Time:
2-5 days

Days Set Up: Monday through Friday

CPT Reflex: Reflex code: 86617 x 2- WB IgG/IgM

CPT Information:
86618 –