Additional Info:
Includes Histoplasma Antibody, Complement Fixation and Histoplasma Antibody, Immunodiffusion
Useful For: Histoplasmosis, caused by infection by H. capsulatum, is usually asymptomatic or mild. Some patients develop chronic pulmonary histoplasmosis or acute disseminated histoplasmosis that is often life-threatening. Complement fixation assesses antibodies to the yeast and mycelial forms. Approximately 90-95% of patients with histoplasmosis have detectable antibodies. Immunodifussion assesses the presence of proteins antigens M and H that often occur independently. Approximately 70% of patients with histoplasmosis have detectable antibodies by immunodifussion.
Methodology: Complement Fixation, Immunodiffusion
Specimen Requirements:
1 yellow-top SST tube (minimum: 0.6 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.
Analytical Time: 3 days
Days Set Up: Tuesday, Thursday, Saturday
CPT Information:
86698 – x 4