A reactive FTA-ABS test confirms the presence of Treponemal Abs, but does not indicate the stage or presence of active infection. The FTA-ABS does not distinguish between syphilis and other treponemal infections. Once the FTA-ABS becomes positive, it remains so for long periods, regardless of therapy. False positive reactions have been associated with diseases with increased or abnormal globulins, patients with lupus erythematosus positive anti-nuclear antibodies (ANA), and during pregnancy.
Methodology: Immunofluorescent Assay (IFA)
Specimen Requirements: 1 yellow-top SST tube (minimum: 0.2 mL of serum). Centrifuge SST 30 minutes after draw. Refrigerate specimen after collection.
• Gross hemolysis, icterus, lipemia, or microbial contamination may interfere.
• Plasma is unacceptable.
Analytical Time: 2 days
Days Set Up: Monday through Friday