The placenta converts DHEA-S produced by the fetal adrenals to Estriol and other estrogens. Estriol is useful in assessing the fetal adrenals and placenta during pregnancy. More commonly, Estriol is one of the maternal serum biochemical markers used to screen for common chromosomal trisomies, especially Down syndrome.
Methodology: Chromatography/Mass Spectrometry
Specimen Requirements: 1 RED TOP tube (minimum: 0.3 mL of serum), centrifuge within 30 minutes after draw. Refrigerate specimen after collection.
Analytical Time: 4 – 6 days
Days Set Up: Monday through Friday