Includes E. chaffeensis IgG Ab and E. chaffeensis IgM Ab.
Two forms, human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE), have been described. E. chaffeensis, which can be detected by an immunofluorescent antibody (IFA) test. Ehrlichia chaffeensis is the etiologic agent of human moncytic ehrlichiosis (HME), and should not be confused with human granulocytic ehrlichiosis (HE), which is caused by the HE agent (not yet fully identified).
Human monocytic ehrlichiosis (HME) is a tick-borne infection caused by Ehrlichia chaffeensis. Infections range in severity from asymptomatic to life-threatening, especially in patients who are immunocompromised. HME is often referred to as spotless or rashless Rocky Mountain spotted fever, and has been reported in various regions of the United States. The causative agent of HME has been identified as Ehrlichia chaffeensis. Infected individuals produce specific antibodies to E. chaffeensis, which can be detected by an immunofluorescent antibody (IFA) test.
Methodology: Indirect Fluorescent Assay
Specimen Requirements: 1 yellow-top SST tube (minimum: 0.2 mL of serum). Centrifuge SST 30 minutes after draw. Aseptically transfer serum to sterile, plastic, screw-capped vial. Refrigerate specimen after collection.
Lavender-top (EDTA plasma) tubes are also acceptable.
Avoid freeze/thaw cycles.
Analytical Time: 2 days
Days Set Up: Monday through Friday
86666 – x 2