Copper is an essential element that is a cofactor of many enzymes. Copper metabolism is disturbed in Wilson’s disease, Menkes disease, primary biliary cirrhosis, and Indian childhood cirrhosis. Copper concentrations increase in acute phase reactions. Copper concentrations are decreased with nephrosis, malabsorption, and malnutrition. Copper concentrations are also useful to monitor patients, especially preterm newborns, on nutritional supplementation. Results of copper are often interpreted together with ceroplasmin.
Methodology: Inductively Coupled Plasma/Mass Spectrometry
Specimen Requirements: 1 royal blue-top (EDTA) Monoject ® tube in trace elements collection package, (minimum: 0.5 mL of EDTA whole blood). Centrifuge and separate RBCs into an acid washed plastic screw-cap vial within 2 hours of collection. Refrigerate specimen after collection.
Patient should refrain from taking vitamins, herbal or mineral supplements at least one week prior to specimen collection.
Analytical Time: 2-5 days
Days Set Up: Sunday, Wednesday, Friday
82525 – Copper