Additional Info: Aldosterone, a steroid hormone secreted by the adrenal cortex, is a mineralocorticoid with the primary function of sodium retention. Approximately 1-2% of individuals with primary hypertension have primary hyperaldosteronism characterized by hypokalemia (low potassium) and low direct renin. Because serum aldosterone concentrations vary due to dietary sodium intake and body position, some physicians prefer measurement of 24-hour urine concentrations for aldosterone.
Methodology: Liquid Chromatography Tandem Mass Spectrometry
1 plain, red-top tube (minimum: 0.5 mL of serum) Centrifuge red-top 30 minutes after draw. Refrigerate specimen after collection.
SST tube is not acceptable.
Draw “upright” samples at least 1/2 hour after patient sits up.
Days Set Up: Sunday through Friday